It makes me laugh out loud, even though he's not referring to me specifically. Of course I'm picturing him saying that in character as Jamie! I think this is the perfect response:
@SamHeughan @bigdoh @MyPeakChallenge 😃😍💜oh yes!! thank YOU Sam Sam Sam on behalf of all fans named KAREN!— karenjeanne☔ (@purpleiris13) March 29, 2017
Yes, I'm a Karen, too, for those of you who don't know. <g> You can follow me on Twitter at @karenh3a.